Fri, 11/21, 7:00 PM, Redman Memorial Stadium, Post
| Cisco | Team | Panhandle |
| Loboes | Mascot | Panthers |
| (10-1) | (Record) | (9-2) |
| Kevin Stennett | Head Coach | Dane Ashley |
| (55-23-0) | Record at School | (95-38-0) |
| (55-23-0) | Coach Career Record | (95-38-0) |
| 39.91 | 2025 Point For Per Game | 59.00 |
| 15 | Class Rank | 1 |
| 15.64 | 2025 Points Against Per Game | 14.00 |
| 12 | Class Rank | 10 |
| 24.27 | 2025 Point Differential Per Game | 45.00 |
| 14 | Class Rank | 2 |
Picks
Masey Ratings – Panhandle by 28
Tony – Panhandle
Antony – Panhandle
Cisco YTD
Week 1 Clyde (L 13-33)
Week 2 San Angelo TLCA (W 39-6)
Week 3 Breckenridge (W 18-14)
Week 4 Coleman (W 23-14)
Week 5 Frenship Memorial (W 65-13)
Week 6 Open
Week 7 Stamford (W 30-20)
Week 8 Abilene TLCA (W 69-8)
Week 9 Hawley (W 29-26)
Week 10 Anson (W 35-14)
Week 11 Olney (W 56-24)
Week 12 Christoval (W 62-0)
Panhandle YTD
Week 1 Clarendon (W 71-0)
Week 2 Stratford (W 61-19)
Week 3 Dalhart (L 35-42)
Week 4 Amarillo River Road (W 77-0)
Week 5 Wellington (W 41-0)
Week 6 Open
Week 7 Sanford-Fritch (W 69-0)
Week 8 Stinnett West Texas (L 49-50)
Week 9 Sunray (W 77-7)
Week 10 Amarillo Highland Park (W 67-6)
Week 11 Spearman (W 67-12)
Week 12 Post (W 35-18)
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